Use of bispecific antibodies to regulate immune responses

A - Human Necessities – 61 – K

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Details

A61K 39/395 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2462883

The invention relates generally to the field of immunology, in particular, to bispecific antibodies. Methods for designing a bispecific antibody for use in treating diseases relating to the immune system are disclosed. Specific examples relate to bispecific antibodies which recognize an activating receptor and an inhibiting receptor.

L'invention concerne généralement le domaine de l'immunologie, et en particulier, des anticorps bispécifiques. L'invention concerne des méthodes permettant de concevoir un anticorps bispécifique à utiliser dans le traitement de maladies concernant le système immunitaire. Des exemples spécifiques concernent des anticorps bispécifiques pouvant reconnaître un récepteur d'activation et un récepteur d'inhibition.

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