Method for stabilization of s-nitrosoglutathione and...

Details Method for stabilization of s-nitrosoglutathione and... Method for stabilization of s-nitrosoglutathione and...

A - Human Necessities

61

K

A61K 9/00 (2006.01)

Patent

CA 2712299

The invention relates to pharmaceutical compositions having alkaline pH comprising S-nitrosoglutathione (GSNO) as active ingredient together with usual additives, optionally with one or more polysaccharide-type polymer(s). Another subject of the invention is a method for stabilizing a solution or non-solid composition containing GSNO wherein the pH of the solution or composition is adjusted to an alkaline value.

La présente invention concerne des compositions pharmaceutiques qui présentent un pH alcalin et qui comprennent du S-nitrosoglutathion (GSNO) en tant qu'ingrédient actif, ainsi que des additifs courants, éventuellement avec un ou plusieurs polymères de type polysaccharide. L'invention concerne également un procédé permettant de stabiliser une solution ou une composition non solide qui contient du GSNO, procédé selon lequel le pH est ajusté à une valeur alcaline.

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