Preparation of n-formyl-l-aspartic anhydride

C - Chemistry – Metallurgy – 07 – D

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260/363.7

C07D 307/66 (2006.01)

Patent

CA 2021178

N-formyl-L-aspartic anhydride is prepared using a minimum excess of formic acid. Acetic anhydride and a C3-C6 secondary alcohol are added to the reaction mixture to consume excess formic acid. The reaction is suitable for further reactions without modification.

De l'anhydride N-formyl-L-aspartique est préparé à l'aide d'un excès minimum d'acide formique. L'anhydride acétique et un alcool secondaire en C3-C6 sont ajoutés au mélange réactionnel pour consommer l'excès d'acide formique. Le mélange réactionnel obtenu peut être utilisé tel quel dans d'autres réactions.

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