C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 217/08 (2006.01) A61K 31/472 (2006.01) A61K 31/4747 (2006.01) A61P 9/00 (2006.01) C07D 221/20 (2006.01)
Patent
CA 2486764
The invention relates to novel substituted tetrahydroisoquinoline derivatives, methods for the production thereof and the use thereof in medicaments, especially as potent PPAR-delta activating compounds for the prophylaxis and/or treatment of cardiovascular diseases, especially dislipidaemia, coronary heart disease and arteriosclerosis.
L'invention concerne de nouveaux dérivés substitués de tétrahydroisoquinoline, des procédés pour leur production, ainsi que leur utilisation dans des médicaments, notamment en tant que composés puissants activant les PPAR delta, pour la prophylaxie ou le traitement de maladies cardio-vasculaires, notamment de dyslipidémies, de maladies cardiaques coronariennes et de l'artériosclérose.
Bischoff Hilmar
Dittrich-Wengenroth Elke
Heckroth Heike
Otteneder Michael
Vaupel Andrea
Bayer Healthcare Ag
Fetherstonhaugh & Co.
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