Phenyl-substituted alkenylcarboxylic acid guanidides,...

Details Phenyl-substituted alkenylcarboxylic acid guanidides,... Phenyl-substituted alkenylcarboxylic acid guanidides,...

C - Chemistry, Metallurgy

07

C

C07C 279/22 (2006.01) A61K 31/16 (2006.01) A61K 31/275 (2006.01) A61K 31/34 (2006.01) A61K 31/38 (2006.01) A61K 31/395 (2006.01) C07C 311/47 (2006.01) C07C 317/32 (2006.01) C07C 323/62 (2006.01) C07D 207/36 (2006.01) C07D 213/65 (2006.01) C07D 295/15 (2006.01) C07D 295/26 (2006.01) C07D 307/58 (2006.01) C07D 333/32 (2006.01)

Patent

CA 2213714

Compounds of the formula I (see formula I) where T is (see formula II) and R(A), R(B), R(C), R(D), R(E), R(F), x and y have the meanings indicated in the claims, and their pharmaceutically acceptable salts are effective inhibitors of the cellular sodium-proton antiporter (Na+/H+ -exchanger). They are therefore outstandingly suitable for treatment of all illnesses which are to be attributed to increased Na+/H+ exchange.

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