B - Operations – Transporting – 01 – D
Patent
B - Operations, Transporting
01
D
B01D 69/14 (2006.01) B01D 69/10 (2006.01) B01J 20/28 (2006.01) G01N 33/18 (2006.01) G01N 33/52 (2006.01)
Patent
CA 2671915
The invention is directed to optical sensors for measuring clinically relevant analytes, their methods of manufacture, and their various uses. In an effort to develop a dry calibration method for the optical sensors of the invention it is discovered that water content inside or in the immediate vicinity of a such a sensor can have a major impact on fluorescence intensity (i.e., a sensor's response in the dry state). Thus, one of the objectives of the invention is the elimination of the bias of sensor responses measured at different humidity environments. The invention concerns a multi-layered laminate comprising inter alia a humidity control layer and a spreading layer. Said layers comprise a water-insoluble porous matrix, including a plurality of channels or through-holes at least some of which extend from one side of the layer to an opposing side, a portion of said holes or channels being filled with a water-soluble, solid, polymeric substance.
L'invention concerne des capteurs optiques servant à mesurer des analytes cliniquement pertinents, ainsi que des procédés de fabrication et diverses utilisations de ces capteurs optiques. Dans le cadre de la mise au point d'un procédé d'étalonnage à sec pour les capteurs optiques selon l'invention, on a découvert que le taux d'humidité à l'intérieur ou à proximité immédiate d'un tel capteur peut avoir un impact majeur sur l'intensité de fluorescence (c.-à-d. une réponse du capteur à l'état sec). Ainsi, l'un des objectifs de l'invention est l'élimination du biais des réponses du capteur mesurées dans différentes conditions d'humidité.
He Huarui
Lin Chao
Ramamurthy Narayanan
Mbm Intellectual Property Law Llp
Opti Medical Systems
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