Hematopoietic growth factor derived from t lymphocytes and...

Details Hematopoietic growth factor derived from t lymphocytes and... Hematopoietic growth factor derived from t lymphocytes and...

C - Chemistry, Metallurgy

12

N

C12N 15/27 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) C07K 1/36 (2006.01) C07K 14/53 (2006.01) C07K 17/00 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2113190

2113190 9300923 PCTABS00019 A T cell-derived colony stimulating factor (TC-CSF) may be isolated from media conditioned with T lymphocyte cells. TC-CSF stimulates formation of colonies composed of granulocytes, macrophages, megakaryocytes, fibrocytic stromal cells, lymphocytes, and mixed colonies of granulocytes and macrophages. Anion exchange chromatography may be employed in conjunction with gel filtration and rpHPLC to isolate TC-CSF. Human TC-CSF and murine TC-CSF cDNA, mRNA, genomic DNA nucleotide and amino acid sequences, expression products, pharmaceutical formulations and antibody materials are specifically provided.

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