Naphthosulfamylmethyl penem antibacterials

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 499/887 (2006.01) A61K 31/43 (2006.01) C07D 499/88 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2333023

The present invention relates to penem antibacterial agents in which the penem nucleus is fused to a 6 membered carbocyclic ring. The compound is further substituted with various substituent groups including at least one cationic group. The compounds are represented by formula (I). Pharmaceutical compositions and methods of use are also included.

La présente invention concerne des agents pénèmes antibactériens dans lesquels le noyau pénème est condensé à un noyau carbocyclique à 6 chaînons. Le composé est ultérieurement substitué par divers groupes substituants, notamment au moins un groupe cationique. Les composés correspondent à la formule (I). L'invention concerne également des compositions pharmaceutiques et des méthodes d'utilisation.

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