Topical endoparasiticide and ectoparasiticide formulations

Details Topical endoparasiticide and ectoparasiticide formulations Topical endoparasiticide and ectoparasiticide formulations

A - Human Necessities

61

K

A61K 31/7048 (2006.01) A61K 31/215 (2006.01) A61K 31/231 (2006.01) A61K 31/365 (2006.01) A61K 31/4402 (2006.01) A61K 31/655 (2006.01) A61P 33/14 (2006.01)

Patent

CA 2579844

A topical formulation having significant parasiticidal activity effective against endoparasites and/or ectoparasites such as heartworms, mites, fleas, ticks, flies is provided, which can be safe to use and avoids the many common deleterious side effects of conventional topical formulations. The topical formulations comprise a combination of a macrocyclic lactone, a neo-nicotinoid and optionally, an insect growth regulator. The topical formulation can be packaged together or packaged so that the macrocyclic lactone and the neo- nicotinoid are stored separately prior to administering the topical insecticide formulation to the animal.

L'invention concerne une formulation topique présentant une activité parasiticide considérable, efficace contre des endoparasites et/ou des ectoparasites, notamment des filaires de chiens, des acariens, des puces, des tiques, des mouches. Cette formulation est inoffensive et permet d'éviter plusieurs effets secondaires nocifs communs des formulations topiques classiques. Les formulations topiques de l'invention comprennent une combinaison de lactose macrocyclique, un néo-nicotinoïde, et éventuellement, un régulateur de croissance d'insecte. La formulation topique peut être conditionnée avec ces substances ou conditionnée de sorte que le lactone macrocyclique et le néo-nicotinoïde soient stockés séparément, avant l'administration de la formulation insecticide topique à l'animal.

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