Methods and compositions for treating bone loss

Details Methods and compositions for treating bone loss Methods and compositions for treating bone loss

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61P 19/10 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2717905

The invention provides methods and compositions for treating, e.g., reducing, bone loss, e.g., cortical bone loss and in particular hand bone loss, comprising administering a TNF.alpha. inhibitor, such as a human TNF.alpha. antibody, or antigen-binding portion thereof.

La présente invention concerne des compositions et des méthodes destinés à traiter la perte osseuse, par exemple la perte osseuse corticale, en la diminuant notamment. Ces compositions et méthodes consistent en l'administration d'un inhibiteur de TNFa, tel quun anticorps TNFa humain, ou dune partie de liaison à lantigène de celui-ci.

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