Human intestinal npt2b

Details Human intestinal npt2b Human intestinal npt2b

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/02 (2006.01) A01K 67/027 (2006.01) A61K 31/00 (2006.01) A61K 38/00 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61P 1/00 (2006.01) A61P 3/02 (2006.01) A61P 3/12 (2006.01) A61P 3/14 (2006.01) A61P 7/08 (2006.01) A61P 13/02 (2006.01) A61P 13/12 (2006.01) A61P 19/00 (2006.01) A61P 19/08 (2006.01) A61P 43/00 (2006.01) C07H 21/00 (2006.01) C07H 21/04 (2006.01) C07K 14/245 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/1

Patent

CA 2296178

A novel human sodium phosphate cotransporter expressed on the apical surface of intestinal epithelial cells (huNpt2B) and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting Npt2B activity in a host and methods of treating disease conditions associated with Npt2B activity.

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