Assay membrane and method of use thereof

Details Assay membrane and method of use thereof Assay membrane and method of use thereof

G - Physics

01

N

G01N 33/53 (2006.01) C40B 30/04 (2006.01) G01N 33/543 (2006.01) C40B 40/00 (2006.01) C40B 40/10 (2006.01)

Patent

CA 2670615

The present invention provides a microporous membrane for detecting at least one target analyte in a sample. The membrane includes an array that comprises at least one capture element and the at least one control element printed on the membrane surface, the at least one capture element corresponding to and being able to bind a target analyte, the plurality of control elements, when present including: i) at least one fiduciary marker, ii) at least one negative control to monitor background signal, iii) at least one negative control to monitor assay specificity, iv) at least one positive colorimetric control, v) at least one positive control to monitor assay performance or any combination thereof.

La présente invention concerne une membrane microporeuse destinée à détecter au moins un analyte cible dans un échantillon. La membrane comprend un réseau qui comporte au moins un élément de capture et le ou les éléments de commande imprimés sur la surface de membrane, le ou les éléments de capture correspondant à et étant capables de se lier à un analyte cible, la pluralité d'éléments de commande, lorsqu'ils sont présents, comprenant : i) au moins un marqueur fiduciaire, ii) au moins un témoin négatif pour surveiller le signal de fond, iii) au moins un témoin négatif pour surveiller la spécificité de dosage, iv) au moins un témoin colorimétrique positif, v) au moins un témoin positif pour surveiller la performance du dosage ou toute combinaison de ceux-ci.

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