A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 38/19 (2006.01) C07K 14/715 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2253557
The present invention is directed to a method of combatting asthma with a composition containing an effective amount of a chimeric TNF.alpha.-binding protein which comprises the soluble part of the p55 TNF receptor and all domains except the first domain of the heavy chain constant region of a human IgG1 or IgG3 and to the use of such a chimeric TNF.alpha.-binding protein for the preparation of a medicament for the treatment of asthma.
La présente invention concerne un procédé permettant de lutter contre l'asthme à l'aide d'une composition contenant une quantité efficace d'une protéine chimère de liaison de TNF.alpha. qui comprend la partie soluble du récepteur TNF p55 et tous les domaines à l'exception du premier domaine de la région constante de la chaîne lourde d'une IgG1 ou d'une IgG3 humaine. La présente invention concerne également l'utilisation de ladite protéine chimère de liaison de TNF.alpha. dans la préparation d'un médicament destiné au traitement de l'asthme.
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
LandOfFree
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