Crystal structure of house dust mite allergen der p 1

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 9/64 (2006.01) A61K 39/35 (2006.01) C07K 1/30 (2006.01) C12N 15/09 (2006.01) C12Q 1/00 (2006.01) C12Q 1/37 (2006.01) G01N 33/566 (2006.01) G01N 33/573 (2006.01) C07K 14/435 (2006.01) C30B 29/58 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2579170

The present invention relates to a crystal structure of house dust mite allergen proDer p 1, the three-dimensional structure of proDer p 1 and the use of the three-dimensional structure to design a mutant of a protein belonging to the papain-like cysteine proteases.

La présente invention concerne une structure cristalline d'allergène d'acarien de poussière de maison proDer p1, la structure tridimensionnelle de proDer p1 et l'utilisation de cette structure tridimensionnelle pour concevoir un mutant d'une protéine appartenant aux cystéine protéases de type papaine.

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