Stabilized pharmaceutical solid compositions of...

A - Human Necessities – 61 – K

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A61K 9/16 (2006.01)

Patent

CA 2551254

Solid compositions with improved physical stability comprise an amorphous, low- solubility drug, a poloxamer, and a stabilizing polymer. The compositions provide good physical stability during storage and concentration enhancement of dissolved drug when administered to an aqueous environment of use.

Compositions solides à stabilité physique améliorée comprenant un médicament amorphe faiblement soluble, un poloxamère, et un polymère stabilisant. Les compositions présentent une bonne stabilité physique lors du stockage et un renforcement de la concentration du médicament dissout lorsque celui-ci est administré dans un milieu aqueux.

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