Methods for increasing cytidine levels in vivo and treating...

Details Methods for increasing cytidine levels in vivo and treating... Methods for increasing cytidine levels in vivo and treating...

A - Human Necessities

61

K

A61K 31/7072 (2006.01) A61K 31/14 (2006.01) A61K 31/24 (2006.01) A61K 31/515 (2006.01) A61K 31/551 (2006.01) A61K 31/685 (2006.01) A61K 31/688 (2006.01) A61K 31/7068 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2339008

Methods of treating certain neurological diseases using exogenous uridine or a uridine source alone as a precursor of endogenous cytidine, particularly in the human brain, are disclosed. Methods are also disclosed wherein exogenous uridine or a uridine source is combined either with drugs increasing uridine availability or with compounds that serve as a source of choline in phospholipid synthesis.

L'invention concerne un procédé permettant de traiter certaines maladies neurologiques, au moyen d'une uridine exogène ou d'une source d'uridine seule, comme précurseur de cytidine endogène, en particulier dans le cerveau humain. L'invention concerne également des procédés où une uridine exogène ou une source d'uridine est associée à des médicaments qui augmentent la disponibilité de l'uridine, ou à des composés qui servent de source de choline dans une synthèse de phospholipides.

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