C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/4439 (2006.01) A61P 3/04 (2006.01) C07D 213/30 (2006.01) C07D 213/61 (2006.01) C07D 405/12 (2006.01) C07D 409/14 (2006.01)
Patent
CA 2559021
The invention relates to alkyne compounds of general formula (I), in which the groups and radicals A, B, W, X, Y, Z, R1 and R2 are defined as cited in claim 1. The invention also relates to medicaments containing at least one inventive alkyne. As a result of the antagonistic action against the MCH-receptor, the inventive medicaments are suitable for treating metabolic disorders and/or eating disorders, in particular adiposity and diabetes.
L'invention concerne des composés d'alcyne de formule générale (I), dans laquelle les groupes et les radicaux A, B, W, X, Y, Z, R?1¿ et R?2¿ ont la signification indiquée dans la revendication 1. L'invention concerne en outre des médicaments contenant au moins une alcyne selon l'invention. En raison de l'effet antagoniste de ces composés vis-à-vis du récepteur MCH, les médicaments selon l'invention sont appropriés pour le traitement de troubles métaboliques et/ou de troubles nutritionnels, notamment de l'adiposité et du diabète.
Lehmann-Lintz Thorsten
Lotz Ralf R. H.
Lustenberger Philipp
Mueller Stephan Georg
Roth Gerald Juergen
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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