Combinations of a cathepsin k inhibitor and a bisphophonate...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/663 (2006.01) A61K 31/451 (2006.01) A61K 31/495 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61P 19/00 (2006.01) A61P 19/10 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01)

Patent

CA 2532948

This invention relates to pharmaceutical preparations comprising certain types of bisphosphonates and certain types of Cathepsin K inhibitors, in particular in the prevention and treatment of bone metastases, tumor-induced hypercalcemia, tumor growth, tumor-induced bone loss and bone loss diseases such as osteoporosis or cancer-therapy-induced bone loss.

Cette invention se rapporte à des préparations pharmaceutiques comprenant certains types de bisphosphonates et certains types d'inhibiteurs de cathepsine K, utilisées notamment dans la prévention et le traitement des métastases osseuses, de l'hypercalcémie induite par une tumeur, de la croissance osseuse, de la perte osseuse induite par tumeur et des maladies avec perte osseuse telles que l'ostéoporose ou avec perte osseuse induite par une thérapie anticancéreuse.

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