Methods and compositions for grafting functional loops into...

Details Methods and compositions for grafting functional loops into... Methods and compositions for grafting functional loops into...

C - Chemistry, Metallurgy

12

N

C12N 9/00 (2006.01) C12N 9/86 (2006.01) C12N 15/09 (2006.01) C12N 15/10 (2006.01) C40B 30/08 (2006.01)

Patent

CA 2488821

The present invention provides targeted enzymes that bind to targets better than the corresponding pre-targeted enzymes bind the target under like conditions, methods of making targeted enzymes, methods of using targeted enzymes to treat diseases, and pharmaceutical compositions comprising targeted enzymes.

L'invention concerne des enzymes ciblés qui se lient à des cibles de façon plus satisfaisante que les enzymes pré-ciblés correspondants ne se lient à la cible dans des conditions analogues. L'invention concerne également des procédés relatifs à l'élaboration d'enzymes ciblés et des procédés relatifs à l'utilisation d'enzymes ciblés pour le traitement de maladies, ainsi que des compositions pharmaceutiques renfermant des enzymes ciblés.

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