C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 229/28 (2006.01) A61K 31/195 (2006.01) C07C 69/608 (2006.01) C07C 205/51 (2006.01) C07C 205/53 (2006.01) C07C 229/34 (2006.01) C07D 209/96 (2006.01) C07D 221/20 (2006.01) C07D 307/94 (2006.01) C07D 311/96 (2006.01)
Patent
CA 2303244
The invention is a novel series of cyclic amino acids which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritable bowel syndrome (IBS), and inflammation, especially arthritis. A pharmaceutical composition containing a compound of the invention as well as methods of preparing the compounds and novel intermediates useful in the preparation of the final compounds are included.
Cette invention a trait à une nouvelle série d'acides aminés efficaces dans le traitement de l'épilepsie, d'accès de lipothymie, de troubles neurodégénératifs, de dépressions, de l'anxiété, de crises de terreur panique, de troubles neuropathologiques et d'affections gastro-intestinales telles que le syndrome du côlon irritable, ainsi que d'inflammations, l'arthrite notamment. Elle concerne également des compositions pharmaceutiques contenant un composé de l'invention et des techniques de préparation de ces composés ainsi que de nouveaux intermédiaires servant à l'élaboration du composé final.
Bryans Justin Stephen
Horwell David Christopher
Thorpe Andrew John
Wustrow David Juergen
Yuen Po-Wai
Macrae & Co.
Warner-Lambert Company
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