A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01) A61K 47/02 (2006.01) A61K 47/04 (2006.01) A61P 27/02 (2006.01) A61P 27/16 (2006.01) B32B 5/16 (2006.01) B32B 15/02 (2006.01) B32B 17/02 (2006.01) B32B 21/02 (2006.01) A61K 31/575 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2467763
The use of nanoparticles of inorganic materials (e.g., synthetic smectite clays) in ophthalmic and otic pharmaceutical compositions is described. The nanoparticles are utilized as biologically inert carriers or depots for ophthalmic and otic drugs. The nanoparticles may also be utilized to modify the rheological properties of the compositions, so as to enhance the viscosity or flow characteristics of the compositions and/or increase the retention time of the compositions in the eye or ear.
La présente invention concerne l'utilisation de nanoparticules de matières inorganiques, notamment des argiles smectiques synthétiques, dans des compositions pharmaceutiques ophtalmiques et otiques. Ces nanoparticules s'utilisent comme des vecteurs ou des dépôts biologiquement inertes pour des médicaments ophtalmiques et otiques. Les nanoparticules permettent également de modifier les propriétés rhéologiques des compositions, de façon à augmenter la viscosité ou les caractéristiques d'écoulement des compositions et/ou augmenter la durée de rétention des compositions dans l'oeil ou l'oreille.
Ketelson Howard Allen
Meadows David L.
Alcon Inc.
Smart & Biggar
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