Gene expression profiling for identification, monitoring,...

Details Gene expression profiling for identification, monitoring,... Gene expression profiling for identification, monitoring,...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2676559

A method is provided in various embodiments for determining a profile data set for a subject with lupus or conditions related to lupus based on a sample from the subject, wherein the sample provides a source of RNAs. The method includes using amplification for measuring the amount of RWA corresponding to at least one constituent from Tables 1-7, 9-13, and 15-20. The profile data set comprises the measure of each constituent, and amplification is performed under measurement conditions that are substantially repeatable.

L'invention concerne divers modes de réalisation d'un procédé destiné à déterminer le profil d'un sujet souffrant de lupus ou de troubles associés au lupus à partir d'un échantillon prélevé sur le sujet, ledit échantillon fournissant une source d'ARN. Le procédé comprend l'utilisation de l'amplification pour mesurer la quantité d'ARN correspondant à au moins un constituant parmi 1-7, 9-13 et 15-20. Le profil comprend la mesure de chaque constituant et l'amplification est réalisée dans des conditions de mesure qui sont sensiblement répétables.

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