Treatment of t-cell lymphoma using...

Details Treatment of t-cell lymphoma using... Treatment of t-cell lymphoma using...

A - Human Necessities

61

K

A61K 31/519 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2565968

T cell lymphoma is treated by administering to a patient suffering from T cell lymphoma a therapeutically effective amount of 10-propargyl-l0- deazaaminopterin. Remission is observed in human patients, even with drug resistant T cell lymphoma at weekly dosages levels as low as 30 mg/m2. In general, the 10-propargyl-l0-deazaaminopterin is administered in an amount of from 30 to 275 mg/m2 per dose.

On traite le lymphome T en administrant à un patient souffrant du lymphome T une quantité thérapeutiquement efficace de 10-propargyl-l0-deazaaminoptérine. On observe une rémission chez des patients humains même avec un lymphome T résistant aux médicaments à des niveaux de posologie quotidiennes ne dépassant pas 30 mg/m?2¿. En général, la 10-propargyl-l0-deazaaminoptérine est administrée selon une quantité allant de 30 à 275 mg/m?2¿ par dose.

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