Treatment of autoimmune disease

Details Treatment of autoimmune disease Treatment of autoimmune disease

A - Human Necessities

61

K

A61K 38/16 (2006.01) A61K 31/44 (2006.01) A61K 38/10 (2006.01) C07K 7/08 (2006.01)

Patent

CA 2698115

The present invention provides compositions, systems, and methods for identifying a patient suffering from and/or susceptible to autoimmune disease who might be likely to respond to treatment with CXCL12 and/or CXCR4 antagonists. The present invention provides novel CXCL12 and/or CXCR4 antagonists, methods of identifying novel CXCL12 and/or CXCR4 antagonists, and methods involving the use of these in the treatment of autoimmune disease.

La présente invention concerne des compositions, des systèmes et des procédés d'identification d'un patient atteint et/ou risquant d'être atteint d'une maladie auto-immune, qui pourrait réagir à un traitement avec des antagonistes de CXCL12 et/ou de CXCR4. Cette invention porte sur de nouveaux antagonistes de CXCL12 et/ou de CXCR4, sur des procédés d'identification de nouveaux antagonistes de CXCL12 et/ou de CXCR4 et sur des procédés impliquant l'utilisation de ces derniers dans le traitement d'une maladie auto-immune.

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