Substituted triazole derivatives as oxytocin antagonists

Details Substituted triazole derivatives as oxytocin antagonists Substituted triazole derivatives as oxytocin antagonists

C - Chemistry, Metallurgy

07

D

C07D 249/08 (2006.01) A61K 31/4196 (2006.01) A61P 5/10 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01)

Patent

CA 2539297

The present invention relates to a class of substituted 1,2,4-triazoles of formula (I) with activity as oxytocin antagonists, uses thereof, processes for the preparation thereof and compositions containing, said, inhibitors. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction, particularly premature ejaculation (P.E.).

L'invention concerne une classe de triazoles-1,2,4 substitués de formule (I) présentant une activité en tant qu'antagonistes de l'oxytocine, leurs utilisations, des procédés pour leur préparation et des compositions contenant lesdits inhibiteurs. Ces inhibiteurs sont utiles dans une grande variété de champs thérapeutiques, y compris les dysfonctionnements sexuels, et notamment l'éjaculation précoce.

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