Sulfonamide derivatives of benzenefused, hydroxy substituted...

C - Chemistry – Metallurgy – 07 – D

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C07D 405/12 (2006.01) A61K 31/425 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07C 311/09 (2006.01) C07D 213/42 (2006.01) C07D 215/18 (2006.01) C07D 241/12 (2006.01) C07D 277/24 (2006.01) C07D 277/28 (2006.01) C07D 277/64 (2006.01) C07D 405/14 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2146261

Compounds of the formula (A), and pharmaceutically acceptable salts and prodrugs thereof, wherein X1, Ar, X, Y1, R1, R2, R3, R5 and n are defined below, which are inhibitors of the production of leukotrienes and/or blockers of leukotriene receptors, methods for preparing said compounds and intermediates useful in the preparation thereof, pharmaceutical com- positions thereof methods of treatment therewith. The compounds of the above formula are useful in the prevention or treat- ment of asthma, arthritis, psoriasis, ulcers, myocardial infarction and related diseases in mammals.

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