A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/7072 (2006.01) A61P 31/20 (2006.01)
Patent
CA 2718175
Compound represented by the formulae: wherein each R individually is H or aliphatic acyl or aromatic acyl group; X is selected from the group consisting of hydrogen, fluoro, chloro, bromo, iodo, alkoxy, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, monoalkylamino, dialkylamino, cyano, aryl and nitro; pharmaceutically acceptable salts thereof, prodrugs thereof and mixtures thereof are used as inhibitors of orthopoxviruses and for treating patients suffering from an orthopoxvirus infection such as, but not limited to, smallpox, cowpox, monkeypox and camelpox.
Cette invention concerne un composé représenté par les formules, chaque R étant individuellement H ou un groupe acyle aliphatique ou aromatique; X étant choisi dans le groupe constitué par hydrogène, fluoro, chloro, bromo, iodo, alcoxy, alkyle, halogénoalkyle, alcényle, halogénoalcényle, alcynyle, amino, monoalkylamino, dialkylamino, cyano, aryle et nitro; leurs sels pharmaceutiquement acceptables, leurs promédicaments et leurs mélanges qui sont utilisés comme inhibiteurs dorthopoxvirus et pour traiter les patients atteints dune infection à orthopoxvirus, notamment la variole, la vaccine, lorthopoxvirus simien et la variole du chameau.
Maddry Joseph A.
Secrist John A. III
Tiwari Kamal N.
Ridout & Maybee Llp
Southern Research Institute
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