Benzo-fused lactams promote release of growth hormone

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 223/16 (2006.01) A23K 1/16 (2006.01) A61K 31/395 (2006.01) A61K 38/28 (2006.01) A61K 38/29 (2006.01) A61K 38/30 (2006.01) C07D 225/06 (2006.01) C07D 267/14 (2006.01) C07D 281/00 (2006.01) C07D 281/10 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07K 5/06 (2006.01) C07K 5/065 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2142707

There are disclosed certain novel compounds identified as benzo-fused lactams which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to increase the stature of those afflicted with a lack of a normal secretion of natural growth hormone. Growth promoting compositions containing such benzo fused lactams as the active ingredient thereof are also disclosed.

On divulgue certains nouveaux composés identifiés comme des lactames fusionnées à un noyau benzène qui favorisent la libération de l'hormone de croissance chez les humains et les animaux. Cette propriété peut être utilisée pour favoriser la croissance des animaux destinés à l'alimentation pour rendre plus efficace la production de produits carnés comestibles, et chez les humains, pour accroître la taille des personnes chez qui l'on observe une carence au niveau de la sécrétion normale de l'hormone de croissance naturelle. On divulgue également des compositions favorisant la croissance contenant de telles lactames fusionnées à un noyau benzène comme ingrédient actif.

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