Treatment of lipid transport and metabolism gene related...

Details Treatment of lipid transport and metabolism gene related... Treatment of lipid transport and metabolism gene related...

C - Chemistry, Metallurgy

12

N

C12N 15/113 (2010.01) A61K 31/713 (2006.01) A61K 48/00 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2761152

The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of a Lipid transport and metabolism gene, in particular, by targeting natural antisense polynucleotides of a Lipid transport and metabolism gene. The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of a Lipid transport and metabolism genes.

La présente invention concerne des oligonucléotides antisens qui modulent l'expression et/ou la fonction d'un gène du métabolisme et du transport des lipides, en particulier, par ciblage de polynucléotides antisens naturels d'un gène du métabolisme et du transport des lipides. L'invention concerne également l'identification de ces oligonucléotides antisens ainsi que leur utilisation dans le traitement de maladies et troubles associés à l'expression d'un gène du métabolisme et du transport des lipides.

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