Mdr1 retroviral plasmid

Details Mdr1 retroviral plasmid Mdr1 retroviral plasmid

C - Chemistry, Metallurgy

12

N

C12N 15/85 (2006.01) C12N 5/10 (2006.01) C12N 15/867 (2006.01)

Patent

CA 2115291

-18- ABSTRACT Existing plasmids, such as pHaMDR/A (available from NIH) are large and cumbersome. The size may limit the known utility of MDR1 as an effective selectable marker in gene transfer experiments. The invention provides novel plasmids including heterologous promoters and cDNA sequences positioned between the retroviral LTRs.

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