Polynucleotides encoding stem cell factor-like proteins

Details Polynucleotides encoding stem cell factor-like proteins Polynucleotides encoding stem cell factor-like proteins

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) C07K 14/52 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) C12N 15/861 (2006.01) C12P 19/34 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2593559

The invention relates to stem cell factor-like proteins SCF A2, SCF A4 or SCF A4v, and polynucleotides encoding the proteins, having gastrointestinal epithelial cell proliferative activity. The invention further relates to the use of pharmaceutical compositions comprising SCF A2, SCF A4 or SCF A4v, for the prevention or treatment of disorders associated with the degeneration of the epithelial mucosa.

L'invention concerne des compositions pharmaceutiques comprenant des polynucléotides et des polypeptides SCFA2, SCFA4 ou SCFA4v de facteurs prolifératifs gastro-intestinaux. L'invention concerne en outre l'utilisation thérapeutique des SCFA2, SCFA4 ou SCFA4v pour prévenir ou traiter des états ou des troubles associés à la dégénérescence de la muqueuse épithéliale .

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