Biologically active agent having immuno-modulating...

A - Human Necessities – 61 – K

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A61K 35/12 (2006.01) A61K 45/00 (2006.01) C07K 2/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2149146

- 77 - A B S T R A C T A biologically active substance having immunomodulating properties, on the basis of organic compounds of the water- soluble hydrolysis products of disintegrated animal tissue, comprised thermostable low-molecular components of morphoplasm and glycocalyx of the cells (CMGC), modified in the processes of embryogenesis and/or proliferation and/or differentiation of the cells, and/or pathology preceding and/or accompanying the process of regeneration and/or reparation of the tissue. A method for producing BAS having immunomodulating properties comprises disintegrating the washed raw material of animal tissue modified. homogenizing, separating non- disintegrated tissue elements by means of centrifugation and/or filtration, isolating supernatant, hydrolyzing said supernatant, separating the hydrolysis products, and collecting resulting supernatant as desired product. A preparation for normalizing physiological state of human and animal organisms, consists of a BAS having immunomodulating properties on the basis of organic compounds, comprising thermostable low-molecular modified CMGC, taken in an amount ranging from about 0.001 to 85.0 per cent by mass with the rest being an excipient. A method for the normalization of physiological state of human and animal organisms stipulates administering a preparation which consists of a BAS having immunomodulating properties on the bests of organic compounds of animal tissue, comprising thermostable low-molecular modified CMGC, taken in an amount ranging from about 0.001 to 85.0 per cent by mass with the rest being an excipient.

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