C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/63 (2006.01) A61K 31/712 (2006.01) C07H 19/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2746001
Oligonucleotide compounds modulate expression and/or function of Sirtuin 1(SIRT1) polynucleotides and encoded products thereof. Methods for treating diseases associated with Sirtuin 1(SIRT1) comprise administering one or more Oligonucleotide compounds designed to inhibit the SIRT1 natural antisense transcript to patients.
L'invention porte sur des composés oligonucléotidiques qui modulent l'expression et/ou la fonction de polynucléotides de sirtuine 1 (SIRT1) et de produits codés par ceux-ci. Les procédés de traitement de maladies associées à sirtuine 1 (SIRT1) comprennent l'administration d'un ou plusieurs composés oligonucléotidiques conçus pour inhiber le transcrit antisens naturel de SIRT1 chez les patients.
Coito Carlos
Collard Joseph
de Leon Belinda
Khorkova Sherman Olga
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Opko Curna Llc
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