Use of myostatin (gdf8) inhibitors in conjunction with...

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/395 (2006.01) A61P 21/00 (2006.01)

Patent

CA 2526669

The disclosure provides methods for treating neuromuscular disorders in mammals. The disclosed methods include administering therapeutically effective amounts of a GDF-8 inhibitor and a corticosteroid to a subject susceptible to, or having, a neuromuscular disorder, so as to maintain desirable levels of muscle function.

L'invention concerne des méthodes de traitement des troubles neuromusculaires chez des mammifères. Les méthodes selon l'invention consistent à administrer des quantités thérapeutiquement efficaces d'un inhibiteur de GDF-8 et d'un corticostéroïde à un sujet souffrant d'un trouble neuromusculaire ou susceptible de développer un tel trouble, de sorte à maintenir la fonction musculaire à un niveau désiré.

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