Cell adhesion inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 275/42 (2006.01) A61K 31/17 (2006.01) A61K 31/195 (2006.01) A61K 31/27 (2006.01) A61K 31/33 (2006.01) A61K 31/66 (2006.01) C07C 237/22 (2006.01) C07C 255/19 (2006.01) C07C 271/22 (2006.01) C07C 275/28 (2006.01) C07C 275/54 (2006.01) C07C 311/06 (2006.01) C07C 311/21 (2006.01) C07C 317/50 (2006.01) C07C 323/59 (2006.01) C07C 323/60 (2006.01) C07D 207/16 (2006.01) C07D 209/42 (2006.01) C07D 213/55 (2006.01) C07D 213/75 (2006.01) C07D 215/48 (2006.01) C07D 277/30 (2006.01) C07D 277/48 (2006.01) C07D 295/1

Patent

CA 2211181

The present invention relates to novel compounds that are useful for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. This invention also relates to pharmaceutical formulations comprising these compounds and methods of using them for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. The compounds and pharmaceutical compositions of this invention can be used as therapeutic or prophylactic agents. They are particularly well-suited for treatment of many inflammatory and autoimmune diseases.

L'invention concerne de nouveaux composés utiles pour inhiber et prévenir l'adhérence cellulaire, ainsi que les pathologies provoquées par l'adhérence cellulaire. Elle concerne également des compositions pharmaceutiques contenant ces composés, ainsi que des procédés permettant de les utiliser pour inhiber et prévenir l'adhérence cellulaire et les pathologies provoquées par l'adhérence cellulaire. On peut utiliser ces composés et ces compositions pharmaceutiques en tant qu'agents thérapeutiques et prophylactiques. Ils sont particulièrement appropriés pour le traitement de nombreuses maladies inflammatoires et auto-immunes.

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