2,5-diaryl tetrahydrofurans and analogs thereof as paf...

Details 2,5-diaryl tetrahydrofurans and analogs thereof as paf... 2,5-diaryl tetrahydrofurans and analogs thereof as paf...

C - Chemistry, Metallurgy

07

D

167/245, 260/361

C07D 307/10 (2006.01) A61K 31/34 (2006.01) A61K 31/665 (2006.01) C07D 307/12 (2006.01) C07F 9/655 (2006.01)

Patent

CA 2018482

58/CCP27 17935IA TITLE OF THE INVENTION NEW 2,5-DIARYL TETRAHYDROFURANS AND ANALOGS THEREOF AX PAF ANTAGONISTS ABSTRACT OF THE DISCLOSURE The present invention is directed to a specifically substituted tetrahydrofuran of the formula (I) Image wherein R4 is an alkylthio, alkylsulfinyl or alkylsulfonyl containing group X is an alkyl or substituted alkyl group. R6 is an alkyl or a substituted alkyl group and the substituents at positions 3, 4 or 5 are acyclic

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