Inhibitors of diacylglycerol acyltransferase (dgat)

Details Inhibitors of diacylglycerol acyltransferase (dgat) Inhibitors of diacylglycerol acyltransferase (dgat)

C - Chemistry, Metallurgy

07

C

C07C 243/36 (2006.01) A61K 31/165 (2006.01) A61K 31/166 (2006.01) A61K 31/277 (2006.01) A61K 31/341 (2006.01) A61K 31/351 (2006.01) A61K 31/381 (2006.01) C07C 243/38 (2006.01) C07C 255/53 (2006.01) C07C 317/22 (2006.01) C07C 321/28 (2006.01) C07D 307/68 (2006.01) C07D 309/08 (2006.01) C07D 333/38 (2006.01) C07D 335/02 (2006.01)

Patent

CA 2596639

Provided herein are compounds of the formula (I), as well as pharmaceutically acceptable salts thereof, wherein R1, R2, R2~, R3, R4, R5 and X are as defined in the specification and claims. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.

L'invention concerne des composés de formule (I), ainsi que des sels pharmaceutiquement acceptables de ces composés, R1, R2, R2', R3, R4, R5 et X étant tels que définis dans la description et les revendications. Ces composés et les compositions pharmaceutiques contenant ces composés sont utiles pour traiter des maladies telles que l'obésité, le diabète sucré de type II et le syndrome métabolique.

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