C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/06 (2006.01) A61K 31/4025 (2006.01) A61K 31/454 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61K 31/55 (2006.01) C07D 403/06 (2006.01) C07D 413/06 (2006.01)
Patent
CA 2503844
The present invention is directed to compounds of the formula (I): (wherein R1, R2, R3, R4, R5, R6, W, X, Z, m and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.
La présente invention concerne des composés représentés par la formule (I): (dans laquelle R¿1?, R¿2?, R¿3?, R¿4?, R¿5?, R¿6?, W, X, Z, m et n sont comme définis dans le descriptif) qui sont utiles comme modulateurs de l'activité de récepteurs de la chimiokine, en particulier du récepteur CCR-2.
Yang Lihu
Zhou Changyou
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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