Pgrp-l polynucleotides, polypeptides, and antibodies

Details Pgrp-l polynucleotides, polypeptides, and antibodies Pgrp-l polynucleotides, polypeptides, and antibodies

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C12N 15/63 (2006.01) C12P 19/34 (2006.01) C12P 21/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2382146

The present invention relates to novel human and murine proteins called PGRP- L, and isolated polynucleotides en- coding these proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing this human protein. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to this novel human protein.

La présente invention concerne de nouvelles protéines humaines et murines appelées PGRP-L et des polynucléotides isolés codant ces protéines. On décrit également des vecteurs, des cellules hôtes, des anticorps et des procédés de recombinaison utiles pour produire cette protéine humaine; ainsi que des procédés de diagnostic et de thérapie utiles pour diagnostiquer et traiter des troubles liés à cette nouvelle protéine humaine.

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