Vaccines and immunotherapeutics using il-28 and compositions...

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61K 39/285 (2006.01) A61P 37/04 (2006.01) C12N 7/01 (2006.01) C12N 15/24 (2006.01)

Patent

CA 2720168

Compositions, recombinant vaccines and live attenuated pathogens comprising one or more isolated nucleic acid molecules that encode an immunogen in combination with an isolated nucleic acid molecule that encodes IL-28 or a functional fragment thereof are disclosed. Methods of inducing an immune response in an individual against an immunogen, using such com-positions are disclosed.

La présente invention concerne des compositions, des vaccins recombinants et des pathogènes vivants atténués comprenant une ou plusieurs molécules dacide nucléique isolées qui codent pour un immunogène en combinaison avec une molécule dacide nucléique isolée qui code pour lIL-28 ou un fragment fonctionnel de celle-ci. La présente invention concerne des procédés dinduction dune réponse immunitaire chez un individu contre un immunogène, en utilisant ces compositions.

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