Influenza vaccine regimens for pandemic-associated strains

A - Human Necessities – 61 – K

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A61K 39/145 (2006.01)

Patent

CA 2752039

In contrast to known regimens where pandemic-associated antigens are given 3-4 weeks apart for immunisation, according to the invention two doses of a pandemic-associated antigen are administered to a human 1 week apart, 2 weeks apart or 6 weeks apart. Thus the invention provides a method for immunizing a human, comprising steps of: (a) administering to the hu-man a first vaccine comprising antigen from a pandemic-associated influenza virus strain; and then 1/2/6 week(s) later, (b) admin-istering to the same human a second influenza vaccine comprising antigen from the pandemic-associated influenza virus strain.

La présente invention concerne l'administration, à un homme, de deux doses d'un antigène associé à une pandémie à une, deux ou six semaines d'intervalle, contrairement à des régimes connus pour lesquels des antigènes associés à une pandémie sont administrés à 3 ou 4 semaines d'intervalle en vue d'une immunisation. Ainsi, l'invention porte sur une méthode d'immunisation pour l'homme, comprenant les étapes suivantes : (a) administration à un homme d'un premier vaccin comprenant un antigène provenant d'une souche d'un influenzavirus associé à une pandémie ; puis 1/2/6 semaine(s) plus tard, (b) administration au même homme d'un second vaccin antigrippal comprenant un antigène provenant de la souche de l'influenzavirus associé à une pandémie.

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