Substituted tetrahydroisoquinoline compounds, their...

C - Chemistry – Metallurgy – 07 – D

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C07D 217/04 (2006.01) A61K 31/4725 (2006.01) A61P 3/00 (2006.01) C07D 217/06 (2006.01) C07D 217/10 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2647024

The present invention relates to substituted tetrahydroisoquinoline compounds of general formula (I), a process for their preparation, medicaments comprising said substituted tetrahydroisoquinoline compounds as well as the use of said substituted tetrahydroisoquinoline compounds for the preparation of medicaments, which are particularly suitable for the prophylaxis and/or treatment of disorders or diseases that are at least partially mediated via 5-HT6 receptors.

La présente invention concerne des composés de tétrahydroisoquinoléine substitués répondant à la formule générale (I), un procédé permettant leur préparation, des médicaments contenant lesdits composés de tétrahydroisoquinoléine substitués, aussi bien que l'utilisation desdits composés de tétrahydroisoquinoléine substitués pour la préparation de médicaments, lesquels sont particulièrement appropriés à la prophylaxie et/ou au traitement de troubles ou de maladies au moins partiellement médiés par les récepteurs 5-HT6.

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