Methods and apparatus for molecular characterization

G - Physics – 01 – N

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G01N 21/49 (2006.01) G01N 21/03 (2006.01) G01N 21/53 (2006.01) G01N 30/74 (2006.01)

Patent

CA 2117475

A molecular characterization detector (8) includes a scattering cell (10) containing a sample for molecular characterization a light source (20) for directing a light beam through the cell (10) so that the light beam is scattered by the sample, optical elements (30, 32, 50, 52) for selecting from the scattered light a measurement beam (40) comprising light that is scattered by the sample from a predetermined portion of the cell (10) in a predetermined range of angles relative to the optical axis (22), and a detector (44) for detecting the measurement beam and providing an output electrical signal representative of the measurement beam. The detector (44) typically selects light scattered from a central portion of the scattering cell at angles in the range of 14° to 16° . A single spherical lens (18) is preferably utilized. As a result, interference from stray scattered light is minimized. A beam dump (24) attenuates the light beam after it passes through the scattering cell (10). Additional detectors (62, 70, 80) detect light scattered at 90° to the light beam. The outputs of the detectors (44, 62, 70, 80) are processed to provide molecular characterization of the sample.

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