C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G06F 17/30 (2006.01) G06F 17/50 (2006.01)
Patent
CA 2321226
The invention concerns the genomic sequence of the FLAP gene. The invention also concerns biallelic markers of a FLAP gene and the association established between these markers and diseases involving the leukotriene pathway such as asthma. The invention provides means to determine the predisposition of individuals to diseases involving the leukotriene pathway as well as means for the diagnosis of such diseases and for the prognosis/detection of an eventual treatment response to agents acting on the leukotriene pathway.
L'invention concerne la séquence génomique du gène FLAP. L'invention concerne également des marqueurs bialléliques d'un gène FLAP et l'association établie entre ces marqueurs et des maladies telles que l'asthme qui affectent la voie des leucotriènes. L'invention propose des moyens permettant de déterminer la prédisposition de certains individus aux maladies affectant la voie des leucotriènes ainsi qu'un moyen pour diagnostiquer ces maladies et pour prévoir ou détecter une réponse visant en définitive les agents agissant dans la voie des leucotriènes.
Blumenfeld Marta
Bougueleret Lydie
Chumakov Ilya
Genset S.a.
Serono Genetics Institute S.a.
Sim & Mcburney
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