Production of growth hormone in transgenic animal milk

C - Chemistry – Metallurgy – 12 – N

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C12N 15/18 (2006.01) A01K 67/027 (2006.01) C04B 41/50 (2006.01) C07K 14/61 (2006.01) C12N 15/85 (2006.01) C12N 15/89 (2006.01)

Patent

CA 2065866

2065866 9103551 PCTABS00003 DNA coding for human growth hormone was linked to mouse whey acid protein promoter fragment and microinjected into fertilized mouse ova. Females of the resulting transgenic mice were mated. After completion of gestation and birth of the litter, the milk from the mothers was assayed and found to contain human growth hormone.

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