The use of sirna silencing in the prevention of metastasis

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) A61K 31/713 (2006.01) A61P 35/04 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2534996

The present invention relates to synthesised RNAs, more specifically short interfering RNAs (siRNAs) that are able to modulate the expression of Tissue Factor (TF) and the use thereof in the prevention of metastasis and treatment of cancer.

L'invention concerne des ARN de synthèse et plus précisément des petits ARN interférants (siRNA), aptes à moduler l'expression du facteur tissulaire (TF), ainsi que leur utilisation pour prévenir la formation de métastases et traiter le cancer.

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