Two-phase matrix for sustained release drug delivery device

Details Two-phase matrix for sustained release drug delivery device Two-phase matrix for sustained release drug delivery device

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61K 9/14 (2006.01) A61K 31/38 (2006.01) A61K 31/415 (2006.01) A61K 31/55 (2006.01) A61K 47/06 (2006.01) A61K 47/08 (2006.01)

Patent

CA 2145631

A two-phase hydrophilic drug-containing matrix for use in transdermal drug delivery patches (10) in which one phase is a continuous hydrophobic polymer phase which optionally includes a hydrophobic solvent that acts as a skin permeation enhancer and the other phase is a dispersed particulate hydrated inorganic silicate in whose absorbed aqueous phase the drug is dissolved. A simple transdermal patch structure (10) contains a backing layer (11), a matrix layer (12) and a release liner layer (13) as com- ponents.

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