Use of cyclopamine in the treatment of psoriasis

Details Use of cyclopamine in the treatment of psoriasis Use of cyclopamine in the treatment of psoriasis

A - Human Necessities

61

K

A61K 31/4355 (2006.01) A61K 8/63 (2006.01) A61P 17/06 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2452152

This invention relates to the use of cyclopamine in the treatment of psoriasis and achievement of rapid clearance of the psoriatic lesions from the skin of patients with no detectable side effects. Disappearances of the clinical signs of psoriasis, including the erythema and scaling, from the skin of patients are accompanied by the reversions of histopathological signs to normalcy and are achievable by topical treatment as fast as within a day. These features make the use of cyclopamine highly desirable in the treatment of psoriasis.

L'invention concerne l'utilisation de la cyclopamine dans le traitement du psoriasis et la réalisation de la disparition rapide de lésions psoriasiques de la peau des patients, sans effet secondaire détectable. La disparition des signes cliniques du psoriasis, y compris l'érythème et la desquamation, de la peau des patients est accompagnée du retour à la normale des signes histopathologiques, et peut être obtenue par traitement local en moins d'une journée. Ces caractéristiques rendent très souhaitable l'utilisation de la cyclopamine dans le traitement du psoriasis.

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