Adjuvant combination formulations

Details Adjuvant combination formulations Adjuvant combination formulations

A - Human Necessities

61

K

A61K 39/39 (2006.01) A61K 39/00 (2006.01) A61K 39/21 (2006.01) A61P 25/18 (2006.01) A61P 31/00 (2006.01) A61P 31/18 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2429000

The use of an aminoalkyl glucosamine phosphate compound, or a derivative or analog thereof, in combination with a cytokine or lymphokine such as granulocyte macrophage colony stimulating factor or interleukin-12, is useful as an adjuvant combination in an antigenic composition to enhance the immune response in a vertebrate host to a selected antigen.

L'invention concerne l'utilisation d'un composé d'aminoalkyle glucosamine phosphate, ou un dérivé ou analogue de ce dernier, en combinaison avec une cytokine ou lymphokine, notamment un facteur stimulant les colonies de granulocytes macrophages ou l'interleukine-12. Cette préparation est utilisée comme combinaison d'adjuvants dans une composition antigénique en vue d'améliorer, chez un vertébré, la réponse immunitaire à un antigène choisi.

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