Oligo(ethylene glycol)-terminated 1,2-dithiolanes and their...

A - Human Necessities – 61 – K

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Details

A61K 47/48 (2006.01) A61K 31/4535 (2006.01) A61K 31/50 (2006.01) A61K 31/60 (2006.01) A61K 31/7088 (2006.01) A61K 31/795 (2006.01) A61K 38/00 (2006.01) A61K 38/28 (2006.01) A61K 38/43 (2006.01) A61K 47/02 (2006.01) A61K 47/30 (2006.01) C08L 71/00 (2006.01)

Patent

CA 2459836

The present invention provides biotechnologically useful oligo(ethylene glycol)-terminated 1,2-dithiolane compositions and conjugates of these compositions with biological or non-biological receptor, ligand, sequestering, or reporter moieties. The invention also provides methods for the preparation of these compositions. Further, the invention provides self-assembled monolayer (SAM) compositions on a metal and methods for their preparation.

L'invention concerne des compositions de 1,2-dithiolane à terminaison oligo(éthylène glycol) et leurs conjugués biotechnologiquement utiles qui présentent des fragments de ligand, de récepteur, des fragment séquestrant ou rapporteurs biologiques ou non biologiques. L'invention concerne également des procédés de préparation desdites compositions. L'invention concerne en outre des compositions de monocouche (SAM) auto-assemblée sur un métal et leurs procédés de préparation.

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